DNA

Part:BBa_K4612104:Design

Designed by: Zibin Chu   Group: iGEM23_BUCT-China   (2023-08-20)


SIGLEC1_Target_5


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]


Design Notes

The length of the DNA was chosen to ensure that it had specificity in human genes, and it was calculated that the length needed to be 30 to ensure this.


Source

From SIGLEC1.

References

1.Pino, M., Erkizia, I., Benet, S. et al. HIV-1 immune activation induces Siglec-1 expression and enhances viral trans-infection in blood and tissue myeloid cells. Retrovirology 12, 37 (2015). 2.Chang YC, Nizet V. Siglecs at the Host-Pathogen Interface. Adv Exp Med Biol. 2020;1204:197-214. doi: 10.1007/978-981-15-1580-4_8. PMID: 32152948; PMCID: PMC7121523.